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ea0013p176 | Diabetes, metabolism and cardiovascular | SFEBES2007

Reduced telomere length, a marker of biological senescence, is inversely correlated with triglycerides and cholesterol in South Asian male type 2 diabetic patients

da Silva Nancy F , Hill Margaret J , Miller Michelle A , Cappuccio Francesco P , Kelly Marilynn A , O’Hare Joseph P , Barnett Anthony H , McTernan Philip G , Kumar Sudhesh

South Asian people have a lower threshold for obesity related complications than Caucasians and as a result have a higher risk of type 2 diabetes (T2DM) and cardiovascular disease (CVD) for a given BMI. Premature biological ageing, assessed by reduction in telomere length (TL), may be mediated by factors resulting from altered metabolic profiles associated with obesity and insulin resistance. We therefore hypothesised that IR is associated with altered metabolic profiles and t...

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Endocrine Abstracts

Reduced telomere length, a marker of biological senescence, is inversely correlated with triglycerides and cholesterol in South Asian male type 2 diabetic patients

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